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Merck

ARHGAP8

Rho GTPase activating protein 8

Sinónimos:
BPGAP1, PP610
Especie:
ID UniProtKB:
ID del gen:
  • Human(23779) Summary: This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
  • Mouse(73167) Rho GTPase activating protein 8
  • Rat(300115) Rho GTPase activating protein 8
  • naked mole-rat(101703941) Rho GTPase activating protein 8
  • domestic guinea pig(100723032) Rho GTPase activating protein 8
  • chicken(418239) Rho GTPase activating protein 8
  • dog(100533462) Rho GTPase activating protein 8
  • domestic cat(101094114) Rho GTPase activating protein 8

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ARHGAP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Arhgap8,
Especie
mouse
MISSION® esiRNA, targeting human ARHGAP8, PRR5-ARHGAP8,
Especie
human