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Merck

APPL1

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

Sinónimos:
APPL, DIP13alpha
Especie:
ID UniProtKB:
ID del gen:
  • Human(26060) Summary: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
  • Mouse(72993) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Rat(290537) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Zebrafish(571540) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • chicken(416002) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • domestic cat(101096960) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • cow(517850) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Horse(100058653) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • dog(484716) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • naked mole-rat(101703342) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • domestic guinea pig(100724445) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • sheep(101109218) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Domestic Rabbit(100353097) adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ANTI-APPL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Ani-APPL1 Antibody, clone 2K17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-APPL1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
western blot
Anti-APPL1 Antibody, clone 4M5X9, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Appl1,
Especie
mouse
MISSION® esiRNA, targeting human APPL1,
Especie
human