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Merck

ADORA3

adenosine A3 receptor

Sinónimos:
A3AR, AD026, bA552M11.5
Especie:
ID UniProtKB:
ID del gen:
  • Human(140) Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11542) adenosine A3 receptor
  • Rat(25370) adenosine A3 receptor
  • chicken(373956) adenosine A3 receptor
  • domestic cat(101094689) adenosine A3 receptor
  • dog(403805) adenosine A3 receptor
  • cow(780806) adenosine A3 receptor
  • sheep(443330) adenosine A3 receptor
  • Domestic Rabbit(100008725) adenosine A3 receptor
  • naked mole-rat(101697269) adenosine A3 receptor
  • domestic guinea pig(100725432) adenosine A3 receptor

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Adenosine, ,
Especie
human
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Especie
human
Adenosine, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Adenosine, phyproof® Reference Substance,
Especie
human
Adenosine, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
VUF 5574, ,
Especie
human
Tyramine hydrochloride, ≥98%,
Especie
human
(S)-(−)-Bay K8644, ≥98% (HPLC), solid,
Especie
human, rat
3-Deazaadenosine, ,
Especie
rat
Caffeine, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ADORA3 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
EHNA hydrochloride, ≥98% (HPLC),
Especie
human
Dilazep dihydrochloride, powder,
Especie
human
5′-Deoxy-5′-(methylthio)adenosine, ,
Especie
human, rat, mouse
α-Naphthoflavone, ≥98%,
Especie
human, rat
Galangin, autophagy inducing flavonoid,
Especie
human, rat

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
2-Chloro-2′-deoxyadenosine, antileukemic,
Especie
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Especie
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
Especie
human, rat
Adenosine, ≥99%,
Especie
human, rat
Theophylline, anhydrous, ≥99%, powder,
Especie
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
2-Iodoadenosine, 97%,
Especie
human, rat
2-Fluoroadenine-9-β-D-arabinofuranoside, DNA synthesis and methylation inhibitor,
Especie
rat, human
2-Fluoroadenosine, 97%,
Especie
rat, human
2-Chloroadenosine, ,
Especie
human, rat
Chloro-IB-MECA, solid, ≥98% (HPLC),
Especie
human, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ADORA3,
Especie
human
MISSION® esiRNA, targeting human TMIGD3,
Especie
human