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Merck

ACTA1

actin, alpha 1, skeletal muscle

Sinónimos:
ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3
Especie:
ID UniProtKB:
ID del gen:
  • Human(58) Summary: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
  • Mouse(11459) actin, alpha 1, skeletal muscle
  • Rat(29437) actin, alpha 1, skeletal muscle
  • chicken(421534) actin, alpha 1, skeletal muscle
  • Horse(100065454) actin, alpha 1, skeletal muscle
  • cow(281592) actin, alpha 1, skeletal muscle
  • domestic cat(101095439) actin, alpha 1, skeletal muscle
  • dog(488984) actin, alpha 1, skeletal muscle
  • naked mole-rat(101721383) actin, alpha 1, skeletal muscle
  • domestic guinea pig(100716933) actin, alpha 1, skeletal muscle
  • sheep(101107662) actin, alpha 1, skeletal muscle

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Actin (α-Sarcomeric) antibody, Mouse monoclonal, ~1.0 mg/mL, clone 5C5, purified from hybridoma cell culture,
Reactividad de especies
bovine, carp, frog, guinea pig, human, rabbit, rat, sheep, snake
Aplicación
ELISA
immunohistochemistry

western blot
Anti-ACTIN-α-1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Anti-Actin-pan antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti--actina antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
amoeba, chicken, human, slime mold, vertebrates, wide range
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-Actin (20-33) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
invertebrates, wide range
Aplicación
immunofluorescence
immunohistochemistry

microarray

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ACTA1,
Especie
human