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Merck

ABCG2

ATP-binding cassette, sub-family G (WHITE), member 2

Sinónimos:
ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1
Especie:
Human ABCG2 (9429), Mouse Abcg2 (26357), Rat Abcg2 (312382), chicken ABCG2 (423767), cow ABCG2 (536203), Horse ABCG2 (100034164), domestic cat ABCG2 (101094017), dog ABCG2 (478472), domestic guinea pig Abcg2 (100723442), Goat ABCG2 (100860857) ...Más
ID UniProtKB:
Q9UNQ0, A0A1W3, A8K1T5, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64
ID del gen:
  • Human(9429) Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(26357) ATP-binding cassette, sub-family G (WHITE), member 2
  • Rat(312382) ATP-binding cassette, subfamily G (WHITE), member 2
  • chicken(423767) ATP-binding cassette, sub-family G (WHITE), member 2
  • cow(536203) ATP-binding cassette, sub-family G (WHITE), member 2
  • Horse(100034164) ATP-binding cassette, sub-family G (WHITE), member 2
  • domestic cat(101094017) ATP-binding cassette, sub-family G (WHITE), member 2
  • dog(478472) ATP-binding cassette, sub-family G (WHITE), member 2
  • domestic guinea pig(100723442) ATP-binding cassette, sub-family G (WHITE), member 2
  • Goat(100860857) ATP-binding cassette, sub-family G (WHITE), member 2
  • sheep(780508) ATP-binding cassette, sub-family G (WHITE), member 2
  • Domestic Rabbit(100008640) ATP-binding cassette, sub-family G (WHITE), member 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ZRB1217
Anti-BCRP (ABCG2) Antibody, clone 10K5 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry
western blot
SAB5701106
Anti-ABCG2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
SAB5700094
Anti-ABCG2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
B7185
Anti-Breast Cancer Resistance Protein antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot

Cell Lines

Referencia del producto
Descripción
Especie
SBVT30
SB-cyBcrp-HEK293, ,
Especie

Proteins

Referencia del producto
Descripción
Especie
SBPE05
SB-BCRP-M-PREDEASY-ATPase kit, membrane based kit for Human BCRP ATPase Transport Assays,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU012921
MISSION® esiRNA, targeting human ABCG2,
Especie
human
EMU090051
MISSION® esiRNA, targeting mouse Abcg2,
Especie
mouse