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Merck

ABCD4

ATP-binding cassette, sub-family D (ALD), member 4

Sinónimos:
ABC41, EST352188, MAHCJ, P70R, P79R, PMP69, PXMP1L
Especie:
ID UniProtKB:
ID del gen:
  • Human(5826) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]
  • Mouse(19300) ATP-binding cassette, sub-family D (ALD), member 4
  • Rat(299196) ATP-binding cassette, subfamily D (ALD), member 4
  • Zebrafish(767748) ATP-binding cassette, sub-family D (ALD), member 4
  • chicken(423349) ATP-binding cassette, sub-family D (ALD), member 4
  • cow(528646) ATP-binding cassette, sub-family D (ALD), member 4
  • Horse(100056775) ATP-binding cassette, sub-family D (ALD), member 4
  • domestic cat(101091287) ATP-binding cassette, sub-family D (ALD), member 4
  • dog(490781) ATP-binding cassette, sub-family D (ALD), member 4
  • domestic guinea pig(100722270) ATP-binding cassette, sub-family D (ALD), member 4
  • naked mole-rat(101701894) ATP-binding cassette, sub-family D (ALD), member 4
  • sheep(101106333) ATP-binding cassette, sub-family D (ALD), member 4

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ABCD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ABCD4,
Especie
human
MISSION® esiRNA, targeting mouse Abcd4,
Especie
mouse