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Merck

ZYX

zyxin

Synonyms:
ESP-2, HED-2
Species:
UniProtKB ID:
Gene ID:
  • Human(7791) Summary: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(22793) zyxin
  • Rat(114636) zyxin
  • fruit fly(317824) Zyxin
  • dog(482736) zyxin
  • domestic cat(101099953) zyxin
  • Zebrafish(564246) zyxin
  • chicken(418300) zyxin
  • cow(768226) zyxin
  • sheep(101123626) zyxin
  • domestic guinea pig(100727523) zyxin
  • naked mole-rat(101710025) zyxin

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ZYX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-ZYX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Zyxin Antibody, clone 4F9P3, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunofluorescence
western blot
Anti-Zyxin Antibody, clone 2F17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-Zyxin antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
Monoclonal Anti-ZYX antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2502, purified immunoglobulin, buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Zyx,
Species
mouse