TK2
thymidine kinase 2, mitochondrial
MTDPS2, MTTK
Human TK2 (7084), Mouse Tk2 (57813), Rat Tk2 (291824), Zebrafish tk2 (437016), domestic cat TK2 (101085008), Horse TK2 (100065312), dog TK2 (611387), chicken TK2 (427551), naked mole-rat Tk2 (101704299), domestic guinea pig Tk2 (100727406) ...More
- Human(7084) Summary: This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. [provided by RefSeq, Dec 2012]
- Mouse(57813) thymidine kinase 2, mitochondrial
- Rat(291824) thymidine kinase 2, mitochondrial
- Zebrafish(437016) thymidine kinase 2, mitochondrial
- domestic cat(101085008) thymidine kinase 2, mitochondrial
- Horse(100065312) thymidine kinase 2, mitochondrial
- dog(611387) thymidine kinase 2, mitochondrial
- chicken(427551) thymidine kinase 2, mitochondrial
- naked mole-rat(101704299) thymidine kinase 2, mitochondrial
- domestic guinea pig(100727406) thymidine kinase 2, mitochondrial
- cow(615457) thymidine kinase 2, mitochondrial
- sheep(101103665) thymidine kinase 2, mitochondrial
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siRNA
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Antibodies
Anti-TK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human, mouse
immunohistochemistry