SNX15
sorting nexin 15
Synonyms:
HSAF001435
Species:
Human SNX15 (29907), Mouse Snx15 (69024), Rat Snx15 (293691), Zebrafish snx15 (393352), domestic cat SNX15 (101082093), dog SNX15 (612080), naked mole-rat Snx15 (101702424), domestic guinea pig Snx15 (100724367), cow SNX15 (507751), Goat SNX15 (100861118)
UniProtKB ID:
Gene ID:
- Human(29907) Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]
- Mouse(69024) sorting nexin 15
- Rat(293691) sorting nexin 15
- Zebrafish(393352) sorting nexin 15
- domestic cat(101082093) sorting nexin 15
- dog(612080) sorting nexin 15
- naked mole-rat(101702424) sorting nexin 15
- domestic guinea pig(100724367) sorting nexin 15
- cow(507751) sorting nexin 15
- Goat(100861118) sorting nexin 15
- sheep(101119948) sorting nexin 15
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SNX15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species