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PRMT1

protein arginine methyltransferase 1

Synonyms:
ANM1, HCP1, HRMT1L2, IR1B4
Species:
UniProtKB ID:
Gene ID:
  • Human(3276) Summary: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
  • Mouse(15469) protein arginine N-methyltransferase 1
  • Rat(60421) protein arginine methyltransferase 1
  • Zebrafish(321974) protein arginine methyltransferase 1
  • dog(476411) protein arginine methyltransferase 1
  • domestic cat(101095389) protein arginine methyltransferase 1
  • Horse(100052097) protein arginine methyltransferase 1
  • cow(520388) protein arginine methyltransferase 1
  • domestic guinea pig(100724273) protein arginine methyltransferase 1
  • naked mole-rat(101721462) protein arginine methyltransferase 1

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PRMT1 antibody produced in mouse, clone GT10111, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-PRMT1 antibody produced in mouse, clone GT779, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Anti-PRMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-PRMT1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-PRMT1 antibody, Mouse monoclonal, clone PRMT1-171, purified from hybridoma cell culture,
Species Reactivity
bovine, canine, chicken, hamster, human, monkey, mouse, rat
Application
ELISA
immunoprecipitation (IP)

western blot

Proteins

Product Number
Description
Species
PRMT1 human, recombinant, expressed in E. coli, ≥50% (SDS-PAGE),
Species
human
PRMT1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Species
human
PRMT1 from rat, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), buffered aqueous solution,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PRMT1,
Species
human
MISSION® esiRNA, targeting mouse Prmt1,
Species
mouse