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Merck

PPBP

pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)

Synonyms:
B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1
Species:
Human PPBP (5473), Mouse Ppbp (57349), Rat Ppbp (246358), dog PPBP (482196), cow PPBP (613723), sheep PPBP (101104151)
UniProtKB ID:
P02775, B2R5F3, Q6IBJ8
Gene ID:
  • Human(5473) Summary: The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. [provided by RefSeq, May 2010]
  • Mouse(57349) pro-platelet basic protein
  • Rat(246358) pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
  • dog(482196) pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
  • cow(613723) pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
  • sheep(101104151) pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
RAB0137
Rat Thymus Chemokine-1 / CXCL7 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
RAB0135
Human NAP-2 / CXCL7 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
RAB0136
Mouse Thymus Chemokine-1 / CXCL7 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
RAB1819
Rhesus Macaque NAP-2 ELISA, for serum, plasma and cell culture supernatants,
Species

Antibodies

Product Number
Description
Species Reactivity
Application
HPA008354
Anti-PPBP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP3121
NAP-2 (CXCL7) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
EHU041701
MISSION® esiRNA, targeting human PPBP,
Species
human
EMU037161
MISSION® esiRNA, targeting mouse Ppbp,
Species
mouse