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Merck

NTRK2

neurotrophic tyrosine kinase, receptor, type 2

Synonyms:
GP145-TrkB, TRKB, trk-B
Species:
UniProtKB ID:
Gene ID:
  • Human(4915) Summary: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18212) neurotrophic tyrosine kinase, receptor, type 2
  • Rat(25054) neurotrophic tyrosine kinase, receptor, type 2
  • sheep(101116015) neurotrophic tyrosine kinase, receptor, type 2
  • Domestic Rabbit(100352548) neurotrophic tyrosine kinase, receptor, type 2
  • naked mole-rat(101720037) neurotrophic tyrosine kinase, receptor, type 2
  • domestic guinea pig(100723565) neurotrophic tyrosine kinase, receptor, type 2
  • chicken(396157) neurotrophic tyrosine kinase, receptor, type 2
  • cow(505824) neurotrophic tyrosine kinase, receptor, type 2
  • Horse(100061700) neurotrophic tyrosine kinase, receptor, type 2
  • domestic cat(101101347) neurotrophic tyrosine kinase, receptor, type 2
  • dog(484147) neurotrophic tyrosine kinase, receptor, type 2

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ELISA

Product Number
Description
Species
Phosphotyrosine NTRK2 / BDNF/NT-3 Growth Factors Receptor ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TrkB antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
human
Application
flow cytometry
western blot
Anti-TRK B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-Trk B (pTyr706/Tyr707) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-phospho-NTRK2 (pTyr515) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
Anti-Trk-B Antibody, clone 2B22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
TrkB/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human
NTRK2/TRKB human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
TRKB (455-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NTRK2,
Species
human
MISSION® esiRNA, targeting mouse Ntrk2,
Species
mouse
MISSION® esiRNA, targeting mouse Ntrk2,
Species
mouse