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Merck

MKNK1

MAP kinase interacting serine/threonine kinase 1

Synonyms:
MNK1
Species:
UniProtKB ID:
Gene ID:
  • Human(8569) Summary: This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(17346) MAP kinase-interacting serine/threonine kinase 1
  • Rat(500526) MAP kinase-interacting serine/threonine kinase 1
  • sheep(101104102) MAP kinase interacting serine/threonine kinase 1
  • domestic guinea pig(100720835) MAP kinase interacting serine/threonine kinase 1
  • naked mole-rat(101723982) MAP kinase interacting serine/threonine kinase 1
  • Zebrafish(555974) MAP kinase interacting serine/threonine kinase 1
  • dog(482509) MAP kinase interacting serine/threonine kinase 1
  • cow(525647) MAP kinase interacting serine/threonine kinase 1
  • domestic cat(101082505) MAP kinase interacting serine/threonine kinase 1
  • chicken(771961) MAP kinase interacting serine/threonine kinase 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Phospho-MKNK1-T197/202 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-MKNK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-MKNK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-MNK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-MNK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

Proteins

Product Number
Description
Species
MNK1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MKNK1,
Species
human
MISSION® esiRNA, targeting mouse Mknk1,
Species
mouse