Skip to Content
Merck

MAP4K5

mitogen-activated protein kinase kinase kinase kinase 5

Synonyms:
GCKR, KHS, KHS1, MAPKKKK5
Species:
UniProtKB ID:
Gene ID:
  • Human(11183) Summary: This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(399510) mitogen-activated protein kinase kinase kinase kinase 5
  • Rat(503027) mitogen-activated protein kinase kinase kinase kinase 5
  • sheep(101103818) mitogen-activated protein kinase kinase kinase kinase 5
  • domestic guinea pig(100727959) mitogen-activated protein kinase kinase kinase kinase 5
  • naked mole-rat(101697393) mitogen-activated protein kinase kinase kinase kinase 5
  • Domestic Rabbit(100346909) mitogen-activated protein kinase kinase kinase kinase 5
  • Zebrafish(334565) mitogen-activated protein kinase kinase kinase kinase 5
  • cow(781335) mitogen-activated protein kinase kinase kinase kinase 5
  • Horse(100066454) mitogen-activated protein kinase kinase kinase kinase 5
  • domestic cat(101095501) mitogen-activated protein kinase kinase kinase kinase 5
  • dog(490685) mitogen-activated protein kinase kinase kinase kinase 5
  • chicken(423576) mitogen-activated protein kinase kinase kinase kinase 5

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MAP4K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-MAP4K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MAP4K5,
Species
human
MISSION® esiRNA, targeting mouse Map4k5,
Species
mouse