IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
Synonyms:
IMPD, IMPD1, LCA11, RP10, sWSS2608
Species:
Human IMPDH1 (3614), Mouse Impdh1 (23917), Rat Impdh1 (362329), sheep IMPDH1 (101104144), Domestic Rabbit IMPDH1 (100357217), domestic guinea pig Impdh1 (100717020), naked mole-rat Impdh1 (101720344), cow IMPDH1 (504305), domestic cat IMPDH1 (101084274), Horse IMPDH1 (100071737)
UniProtKB ID:
Gene ID:
- Human(3614) Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
- Mouse(23917) inosine 5'-phosphate dehydrogenase 1
- Rat(362329) IMP (inosine 5'-monophosphate) dehydrogenase 1
- sheep(101104144) IMP (inosine 5'-monophosphate) dehydrogenase 1
- Domestic Rabbit(100357217) IMP (inosine 5'-monophosphate) dehydrogenase 1
- domestic guinea pig(100717020) IMP (inosine 5'-monophosphate) dehydrogenase 1
- naked mole-rat(101720344) IMP (inosine 5'-monophosphate) dehydrogenase 1
- cow(504305) IMP (inosine 5'-monophosphate) dehydrogenase 1
- domestic cat(101084274) IMP (inosine 5'-monophosphate) dehydrogenase 1
- Horse(100071737) IMP (inosine 5'-monophosphate) dehydrogenase 1
- dog(608783) IMP (inosine 5'-monophosphate) dehydrogenase 1
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