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IL5

interleukin 5 (colony-stimulating factor, eosinophil)

Synonyms:
EDF, IL-5, TRF
Species:
UniProtKB ID:
Gene ID:
  • Human(3567) Summary: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
  • Mouse(16191) interleukin 5
  • Rat(24497) interleukin 5
  • sheep(443350) interleukin 5 (colony-stimulating factor, eosinophil)
  • domestic guinea pig(100135558) interleukin 5
  • naked mole-rat(101719528) interleukin 5 (colony-stimulating factor, eosinophil)
  • chicken(474360) interleukin 5 (colony-stimulating factor, eosinophil)
  • cow(280825) interleukin 5 (colony-stimulating factor, eosinophil)
  • Horse(100034199) interleukin 5 (colony-stimulating factor, eosinophil)
  • domestic cat(493803) interleukin 5 (colony-stimulating factor, eosinophil)
  • dog(403790) interleukin 5 (colony-stimulating factor, eosinophil)

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ELISA

Product Number
Description
Species
Rhesus Macaque IL5 / Interleukin-5 ELISA Kit, ,
Species
Human IL-5 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Mouse IL-5 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Feline IL5 / Interleukin-5 ELISA Kit, ,
Species
domestic cat

Small Molecule - Antagonist

Product Number
Description
Species
Budesonide, ≥99%,
Species
human, rat
Terfenadine, ,
Species
mouse, rat, human
Betamethasone, ≥98%,
Species
mouse, rat, human
Dexamethasone, tested according to Ph. Eur.,
Species
mouse, rat, human
Dexamethasone, meets USP testing specifications,
Species
mouse, rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL-5 Antibody, clone 1B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
ELISA
immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
IL-5 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Interleukin-5 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
mouse
Interleukin-5 human, recombinant, expressed in baculovirus infected Sf21 cells, ≥97% (SDS-PAGE), lyophilized powder, suitable for cell culture,
Species
human
IL-5 from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Il5,
Species
mouse