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HCRT

hypocretin (orexin) neuropeptide precursor

Synonyms:
NRCLP1, OX, PPOX
Species:
UniProtKB ID:
Gene ID:
  • Human(3060) Summary: This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]
  • Mouse(15171) hypocretin
  • Rat(25723) hypocretin
  • Zebrafish(613239) hypocretin (orexin) neuropeptide precursor
  • dog(607641) hypocretin (orexin) neuropeptide precursor
  • chicken(374005) hypocretin (orexin) neuropeptide precursor
  • cow(281222) hypocretin (orexin) neuropeptide precursor
  • sheep(101122291) hypocretin (orexin) neuropeptide precursor
  • domestic guinea pig(100717357) hypocretin (orexin) neuropeptide precursor
  • naked mole-rat(101723299) hypocretin (orexin) neuropeptide precursor

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HCRT, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Anti-HCRT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Proteins

Product Number
Description
Species
Orexin B rat, mouse, ≥97% (HPLC),
Species
mouse, rat
Orexin A human, rat, mouse, ≥97% (HPLC),
Species
mouse, rat, human