GSTM2
glutathione S-transferase mu 2 (muscle)
Synonyms:
GST4, GSTM, GSTM2-2, GTHMUS
Species:
Human GSTM2 (2946), Mouse Gstm2 (14863), Rat Gstm2 (24424), sheep GSTM2 (100294593), Domestic Rabbit GSTM2 (100009073), domestic guinea pig Gstm2 (100379537), domestic guinea pig Gstm2 (100732167), chicken GSTM2 (395976), cow GSTM2 (615537)
UniProtKB ID:
Gene ID:
- Human(2946) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]
- Mouse(14863) glutathione S-transferase, mu 2
- Rat(24424) glutathione S-transferase mu 2
- sheep(100294593) glutathione S-transferase mu 2 (muscle)
- Domestic Rabbit(100009073) glutathione S-transferase mu 2 (muscle)
- domestic guinea pig(100379537) glutathione S-transferase, mu 2
- domestic guinea pig(100732167) glutathione S-transferase mu 2 (muscle)
- chicken(395976) glutathione S-transferase mu 2 (muscle)
- cow(615537) glutathione S-transferase M2
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