GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
Synonyms:
Species:
Human GABRG3 (2567), Mouse Gabrg3 (14407), Rat Gabrg3 (79211), domestic guinea pig Gabrg3 (100729690), naked mole-rat Gabrg3 (101712623), sheep GABRG3 (101108521), Zebrafish gabrg3 (567057), cow GABRG3 (613670), domestic cat GABRG3 (101094182), dog GABRG3 (488685)
UniProtKB ID:
Gene ID:
- Human(2567) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
- Mouse(14407) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
- Rat(79211) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- domestic guinea pig(100729690) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- naked mole-rat(101712623) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- sheep(101108521) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- Zebrafish(567057) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- cow(613670) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- domestic cat(101094182) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- dog(488685) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- chicken(770097) gamma-aminobutyric acid (GABA) A receptor, gamma 3
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Small Molecule - Allosteric Modulator
Product Number
Description
Species
Diazepam for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Oxazepam for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GABRG3 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-GABRG3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species