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Merck

FGFR1OP

FGFR1 oncogene partner

Synonyms:
FOP
Species:
UniProtKB ID:
Gene ID:
  • Human(11116) Summary: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
  • Mouse(75296) Fgfr1 oncogene partner
  • Rat(365103) FGFR1 oncogene partner
  • Zebrafish(415215) FGFR1 oncogene partner
  • chicken(421568) FGFR1 oncogene partner
  • dog(612453) FGFR1 oncogene partner
  • cow(506246) FGFR1 oncogene partner
  • domestic cat(101099885) FGFR1 oncogene partner
  • domestic guinea pig(100728960) FGFR1 oncogene partner
  • naked mole-rat(101707272) FGFR1 oncogene partner
  • sheep(101115039) FGFR1 oncogene partner

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FGFR1OP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-FGFR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Fgfr1op,
Species
mouse
MISSION® esiRNA, targeting human FGFR1OP,
Species
human