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Merck

FBXW11

F-box and WD repeat domain containing 11

Synonyms:
BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos
Species:
UniProtKB ID:
Gene ID:
  • Human(23291) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]
  • Mouse(103583) F-box and WD-40 domain protein 11
  • Rat(303024) F-box and WD repeat domain containing 11
  • chicken(416181) F-box and WD repeat domain containing 11
  • dog(479291) F-box and WD repeat domain containing 11
  • Horse(100069972) F-box and WD repeat domain containing 11
  • cow(540642) F-box and WD repeat domain containing 11
  • domestic cat(101094156) F-box and WD repeat domain containing 11
  • domestic guinea pig(100715997) F-box and WD repeat domain containing 11
  • naked mole-rat(101718253) F-box and WD repeat domain containing 11
  • sheep(101107136) F-box and WD repeat domain containing 11
  • Domestic Rabbit(100340737) F-box and WD repeat domain containing 11

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FBXW11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-FBXW11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ak010033,
Species
mouse
MISSION® esiRNA, targeting human FBXW11,
Species
human
MISSION® esiRNA, targeting mouse Fbxw11,
Species
mouse