DOCK2
dedicator of cytokinesis 2
Synonyms:
Species:
Human DOCK2 (1794), Mouse Dock2 (94176), Rat Dock2 (360509), Zebrafish dock2 (571408), cow DOCK2 (510083), cow DOCK2 (281745), Horse DOCK2 (100070446), domestic cat DOCK2 (101097544), dog DOCK2 (489128), Zebrafish dock2 (100330200) ...More
UniProtKB ID:
Gene ID:
- Human(1794) Summary: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection. [provided by RefSeq, Oct 2011]
- Mouse(94176) dedicator of cyto-kinesis 2
- Rat(360509) dedicator of cytokinesis 2
- Zebrafish(571408) dedicator of cyto-kinesis 2
- cow(510083) dedicator of cytokinesis 2
- cow(281745) dedicator of cytokinesis 2
- Horse(100070446) dedicator of cytokinesis 2
- domestic cat(101097544) dedicator of cytokinesis 2
- dog(489128) dedicator of cytokinesis 2
- Zebrafish(100330200) dedicator of cytokinesis 2
- chicken(427612) dedicator of cytokinesis 2
- sheep(101104011) dedicator of cytokinesis 2
- naked mole-rat(101707633) dedicator of cytokinesis 2
- domestic guinea pig(100714041) dedicator of cytokinesis 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DOCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot