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Merck

ASGR1

asialoglycoprotein receptor 1

Synonyms:
ASGPR, ASGPR1, CLEC4H1, HL-1
Species:
UniProtKB ID:
Gene ID:
  • Human(432) Summary: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(11889) asialoglycoprotein receptor 1
  • Rat(24210) asialoglycoprotein receptor 1
  • dog(489461) asialoglycoprotein receptor 1
  • cow(509121) asialoglycoprotein receptor 1
  • naked mole-rat(101707146) asialoglycoprotein receptor 1
  • domestic guinea pig(100714188) asialoglycoprotein receptor 1
  • sheep(101116157) asialoglycoprotein receptor 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ASGR1 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Anti-ASGR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ASGR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Asgr1,
Species
mouse
MISSION® esiRNA, targeting human ASGR1,
Species
human