ARRB2
arrestin, beta 2
Synonyms:
ARB2, ARR2, BARR2
Species:
Human ARRB2 (409), Mouse Arrb2 (216869), Rat Arrb2 (25388), domestic guinea pig Arrb2 (100716149), naked mole-rat Arrb2 (101709908), sheep ARRB2 (101112493), Domestic Rabbit ARRB2 (100341204), Horse ARRB2 (100072892), domestic cat ARRB2 (101093558), dog ARRB2 (607262)
UniProtKB ID:
Gene ID:
- Human(409) Summary: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
- Mouse(216869) arrestin, beta 2
- Rat(25388) arrestin, beta 2
- domestic guinea pig(100716149) arrestin, beta 2
- naked mole-rat(101709908) arrestin, beta 2
- sheep(101112493) arrestin, beta 2
- Domestic Rabbit(100341204) arrestin, beta 2
- Horse(100072892) arrestin, beta 2
- domestic cat(101093558) arrestin, beta 2
- dog(607262) arrestin, beta 2
- cow(281638) arrestin, beta 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ARRB2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, pig, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-ARRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-ARRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-phospho-β-Arrestin (pSer412) antibody produced in rabbit, affinity isolated antibody, aqueous solution,
Species Reactivity
mouse, rat
Application
western blot