ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
Synonyms:
bHLHe1
Species:
Human ARNT2 (9915), Mouse Arnt2 (11864), Rat Arnt2 (25243), sheep ARNT2 (100135448), domestic guinea pig Arnt2 (100727525), naked mole-rat Arnt2 (101715821), Zebrafish arnt2 (64277), dog ARNT2 (608366), domestic cat ARNT2 (101087746), Horse ARNT2 (100067423) ...More
UniProtKB ID:
Gene ID:
- Human(9915) Summary: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Jul 2008]
- Mouse(11864) aryl hydrocarbon receptor nuclear translocator 2
- Rat(25243) aryl hydrocarbon receptor nuclear translocator 2
- sheep(100135448) aryl-hydrocarbon receptor nuclear translocator 2
- domestic guinea pig(100727525) aryl-hydrocarbon receptor nuclear translocator 2
- naked mole-rat(101715821) aryl-hydrocarbon receptor nuclear translocator 2
- Zebrafish(64277) aryl hydrocarbon receptor nuclear translocator 2
- dog(608366) aryl-hydrocarbon receptor nuclear translocator 2
- domestic cat(101087746) aryl-hydrocarbon receptor nuclear translocator 2
- Horse(100067423) aryl-hydrocarbon receptor nuclear translocator 2
- cow(533445) aryl-hydrocarbon receptor nuclear translocator 2
- chicken(415481) aryl-hydrocarbon receptor nuclear translocator 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ARNT2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence