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Merck

ACTA1

actin, alpha 1, skeletal muscle

Synonyms:
ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3
Species:
UniProtKB ID:
Gene ID:
  • Human(58) Summary: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
  • Mouse(11459) actin, alpha 1, skeletal muscle
  • Rat(29437) actin, alpha 1, skeletal muscle
  • chicken(421534) actin, alpha 1, skeletal muscle
  • Horse(100065454) actin, alpha 1, skeletal muscle
  • cow(281592) actin, alpha 1, skeletal muscle
  • domestic cat(101095439) actin, alpha 1, skeletal muscle
  • dog(488984) actin, alpha 1, skeletal muscle
  • naked mole-rat(101721383) actin, alpha 1, skeletal muscle
  • domestic guinea pig(100716933) actin, alpha 1, skeletal muscle
  • sheep(101107662) actin, alpha 1, skeletal muscle

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Actin-pan antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Actin (α-Sarcomeric) antibody, Mouse monoclonal, ~1.0 mg/mL, clone 5C5, purified from hybridoma cell culture,
Species Reactivity
bovine, carp, frog, guinea pig, human, rabbit, rat, sheep, snake
Application
ELISA
immunohistochemistry

western blot
Anti-ACTIN-α-1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Actin (20-33) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
invertebrates, wide range
Application
immunofluorescence
immunohistochemistry

microarray

western blot
Anti-Actin antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
amoeba, chicken, human, slime mold, vertebrates, wide range
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACTA1,
Species
human