- Improved synthesis of 2,2'-bipyrimidine.
Improved synthesis of 2,2'-bipyrimidine.
The Journal of organic chemistry (2002-08-31)
Gábor Vlád, István T Horváth
PMID12201781
ABSTRACT
A high-yield synthesis was developed for the preparation of 2,2'-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4',6,6'-tetramethyl-2,2'-bipyrimidine (2) and 5,5'-dibromo-2,2'-bipyrimidine (3).
MATERIALS