- Synthesis and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 2-amino-4-hydroxy-delta-valerolactam derivatives.
Synthesis and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 2-amino-4-hydroxy-delta-valerolactam derivatives.
Farmaco (Societa chimica italiana : 1989) (1998-05-15)
S Gordon, L Costa, M Incerti, E Manta, J Saldaña, L Domínguez, R Mariezcurrena, L Suescun
PMID9580122
ABSTRACT
The synthesis of a series of 2-amino-4-hydroxy-delta-valerolactam derivatives is described (compounds 4 to 10). These compounds showed a high anthelmintic in vitro activity against the Nippostrongylus brasiliensis model.
MATERIALS