540250

(S)-(+)-1,2-Propanediol

96%

• Synonym(s): (S)-(+)-Propylene glycerol
• Linear Formula: CH₃CH(OH)CH₂OH
• CAS Number: 4254-15-3
• Molecular Weight: 76.09
• Beilstein: 1718871
• MDL number: MFCD00004539
• UNSPSC Code: 12352001
• PubChem Substance ID: 24878450
• NACRES: NA.22

Properties

• Assay: 96%
• optical activity: [α]20/D +16.5°, neat
• optical purity: ee: 98% (GLC)
• refractive index: n20/D 1.432 (lit.)
• bp: 186-188 °C/765 mmHg (lit.)
• density: 1.036 g/mL at 20 °C (lit.)
• SMILES string: C[C@H](O)CO
• InChI: 1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3/t3-/m0/s1
• InChI key: DNIAPMSPPWPWGF-VKHMYHEASA-N

Description

Application

(S)-(+)-1,2-Propanediol can be used as a reactant to synthesize:

• Optically active chiral (S)-1, 2-propanediol derivatives using mesogenic carboxylic acids via esterification in the presence of dimethylaminopyridine (DMAP) as a catalyst.
• 3,4-Ethylenedioxythiophenes via Mitsunobu reaction.
• Vicinal diol cyclic sulfates in the presence of sodium periodate and ruthenium chloride as catalysts.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 217.4 °F - closed cup
• Flash Point(C): 103 °C - closed cup