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Merck

SRSF2

serine/arginine-rich splicing factor 2

Synonyms:
PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b
Species:
UniProtKB ID:
Gene ID:
  • Human(6427) Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]
  • Mouse(20382) serine/arginine-rich splicing factor 2
  • Rat(494445) serine/arginine-rich splicing factor 2
  • chicken(396195) serine/arginine-rich splicing factor 2
  • dog(612817) serine/arginine-rich splicing factor 2
  • cow(508312) serine/arginine-rich splicing factor 2
  • naked mole-rat(101721554) serine/arginine-rich splicing factor 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SRSF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SFRS2 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, human, mouse, rat, zebrafish
Application
western blot
Anti-Splicing Factor SC-35 antibody, Mouse monoclonal, clone SC-35, purified from hybridoma cell culture,
Species Reactivity
frog, hamster, human, mouse, porcine, quail, rat
Application
ELISA
dot blot

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
ANTI-SFRS2(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-SC-35 Antibody, clone 1SC-4F11, ascites fluid, clone 1SC-4F11, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot

Proteins

Product Number
Description
Species
SC35 human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SRSF2,
Species
human