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Merck

SPARC

secreted protein, acidic, cysteine-rich (osteonectin)

Synonyms:
ON
Species:
UniProtKB ID:
Gene ID:
  • Human(6678) Summary: This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. [provided by RefSeq, Dec 2011]
  • Mouse(20692) secreted acidic cysteine rich glycoprotein
  • Rat(24791) secreted protein, acidic, cysteine-rich (osteonectin)
  • Zebrafish(321357) secreted acidic cysteine rich glycoprotein
  • Horse(100060119) secreted protein, acidic, cysteine-rich (osteonectin)
  • domestic cat(101099861) secreted protein, acidic, cysteine-rich (osteonectin)
  • dog(612159) secreted protein, acidic, cysteine-rich (osteonectin)
  • dog(595143) secreted protein, acidic, cysteine-rich (osteonectin)
  • chicken(386571) secreted protein, acidic, cysteine-rich (osteonectin)
  • domestic guinea pig(100725447) secreted protein, acidic, cysteine-rich (osteonectin)
  • Domestic Rabbit(100009355) secreted protein, acidic, cysteine-rich (osteonectin)
  • naked mole-rat(101697769) secreted protein, acidic, cysteine-rich (osteonectin)
  • cow(282077) secreted protein, acidic, cysteine-rich (osteonectin)
  • Goat(100860800) secreted protein, acidic, cysteine-rich (osteonectin)
  • sheep(100307048) secreted protein, acidic, cysteine-rich (osteonectin)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SPARC (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, sheep, zebrafish
Application
immunohistochemistry
western blot
Anti-SPARC antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-SPARC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-SPARC antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-SPARC antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
SPARC/Osteonectin human, recombinant, expressed in CHO cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SPARC,
Species
human
MISSION® esiRNA, targeting mouse Sparc,
Species
mouse