PTPRO
protein tyrosine phosphatase, receptor type, O
Synonyms:
GLEPP1, NPHS6, PTP-OC, PTP-U2, PTPROT, PTPU2, R-PTP-O
Species:
Human PTPRO (5800), Mouse Ptpro (19277), Rat Ptpro (50677), Zebrafish ptpro (407676), domestic cat PTPRO (101098147), Horse PTPRO (100064067), dog PTPRO (486664), chicken PTPRO (373911), cow PTPRO (541043), naked mole-rat Ptpro (101716353)
UniProtKB ID:
Gene ID:
- Human(5800) Summary: This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]
- Mouse(19277) protein tyrosine phosphatase, receptor type, O
- Rat(50677) protein tyrosine phosphatase, receptor type, O
- Zebrafish(407676) protein tyrosine phosphatase, receptor type, O
- domestic cat(101098147) protein tyrosine phosphatase, receptor type, O
- Horse(100064067) protein tyrosine phosphatase, receptor type, O
- dog(486664) protein tyrosine phosphatase, receptor type, O
- chicken(373911) protein tyrosine phosphatase, receptor type, O
- cow(541043) protein tyrosine phosphatase, receptor type, O
- naked mole-rat(101716353) protein tyrosine phosphatase, receptor type, O
- domestic guinea pig(100714951) protein tyrosine phosphatase, receptor type, O
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PTPRO antibody produced in mouse, clone 3F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-PTPRO antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-GLEPP1/PTPRO Antibody, clone 5C11, clone 5C11, from mouse,
Species Reactivity
human
Application
electron microscopy
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
esiRNA
Product Number
Description
Species