PEX5
peroxisomal biogenesis factor 5
Synonyms:
PBD2A, PBD2B, PTS1-BP, PTS1R, PXR1
Species:
Human PEX5 (5830), Mouse Pex5 (19305), Rat Pex5 (312703), fruit fly Pex5 (31141), Horse PEX5 (100053174), domestic cat PEX5 (101089871), dog PEX5 (486710), chicken PEX5 (418299), Zebrafish pex5 (394131), Thale Cress PEX5 (835728) ...More
UniProtKB ID:
Gene ID:
- Human(5830) Summary: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
- Mouse(19305) peroxisomal biogenesis factor 5
- Rat(312703) peroxisomal biogenesis factor 5
- fruit fly(31141) Peroxin 5
- Horse(100053174) peroxisomal biogenesis factor 5
- domestic cat(101089871) peroxisomal biogenesis factor 5
- dog(486710) peroxisomal biogenesis factor 5
- chicken(418299) peroxisomal biogenesis factor 5
- Zebrafish(394131) peroxisomal biogenesis factor 5
- Thale Cress(835728) peroxin 5
- domestic guinea pig(100135597) peroxisomal biogenesis factor 5
- Domestic Rabbit(100343561) peroxisomal biogenesis factor 5
- naked mole-rat(101700051) peroxisomal biogenesis factor 5
- cow(514832) peroxisomal biogenesis factor 5
- sheep(101105736) peroxisomal biogenesis factor 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PEX5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PEX5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PEX5, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot