MAP2K7
mitogen-activated protein kinase kinase 7
Synonyms:
Jnkk2, MAPKK7, MKK7, PRKMK7, SAPKK-4, SAPKK4
Species:
Human MAP2K7 (5609), Mouse Map2k7 (26400), Rat Map2k7 (363855), Zebrafish map2k7 (560913), dog MAP2K7 (485004), cow MAP2K7 (787278), domestic cat MAP2K7 (101095157), sheep MAP2K7 (100302082), naked mole-rat Map2k7 (101710666), domestic guinea pig Map2k7 (100731057)
UniProtKB ID:
Gene ID:
- Human(5609) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008]
- Mouse(26400) mitogen-activated protein kinase kinase 7
- Rat(363855) mitogen activated protein kinase kinase 7
- Zebrafish(560913) mitogen-activated protein kinase kinase 7
- dog(485004) mitogen-activated protein kinase kinase 7
- cow(787278) mitogen-activated protein kinase kinase 7
- domestic cat(101095157) mitogen-activated protein kinase kinase 7
- sheep(100302082) mitogen-activated protein kinase kinase 7
- naked mole-rat(101710666) mitogen-activated protein kinase kinase 7
- domestic guinea pig(100731057) mitogen-activated protein kinase kinase 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MEK7 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-phospho-MAP2K7 (pThr275) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Monoclonal Anti-MAP2K7 antibody produced in mouse, clone 4E8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Monoclonal Anti-MAP2K7 antibody produced in mouse, clone 2C12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-MAP2K7, (N-terminal) antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
MKK7β1 Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human MKK7β1, amino acids 2-end. For use in Kinase Assays.,
Species
human
MKK7β1 Protein, inactive, 50 g, Unactive, N-terminal GST-tagged, recombinant, human MKK7β1 amino acids 2-end, for use in Kinase Assays.,
Species
human