HHIP
hedgehog interacting protein
Synonyms:
HIP
Species:
Human HHIP (64399), Mouse Hhip (15245), Rat Hhip (291936), sheep HHIP (101111396), Domestic Rabbit HHIP (100344588), domestic guinea pig Hhip (100728644), naked mole-rat Hhip (101724427), Zebrafish hhip (326102), domestic cat HHIP (101087058), cow HHIP (540830) ...More
UniProtKB ID:
Gene ID:
- Human(64399) Summary: This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011]
- Mouse(15245) Hedgehog-interacting protein
- Rat(291936) Hedgehog-interacting protein
- sheep(101111396) hedgehog interacting protein
- Domestic Rabbit(100344588) hedgehog interacting protein
- domestic guinea pig(100728644) hedgehog interacting protein
- naked mole-rat(101724427) hedgehog interacting protein
- Zebrafish(326102) hedgehog interacting protein
- domestic cat(101087058) hedgehog interacting protein
- cow(540830) hedgehog interacting protein
- Horse(100062868) hedgehog interacting protein
- dog(475452) hedgehog interacting protein
- chicken(422460) hedgehog interacting protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-HHIP antibody produced in mouse, clone 5D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HHIP antibody produced in rabbit, ,
Species Reactivity
chicken, human, mouse
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot