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Merck

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

Synonyms:
EIG10, EJM7, GEFSP5
Species:
UniProtKB ID:
Gene ID:
  • Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
  • Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
  • naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta
  • sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
  • Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
  • chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
  • dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
  • cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta

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Small Molecule - Agonist

Product Number
Description
Species
Meprobamate, analytical standard,
Species
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Oxazepam, ,
Species
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
(±)-Lorazepam, ,
Species
human
Clobazam, ,
Species
human
(±)-Thiopental, ,
Species
human
Estazolam, ,
Species
human
Alprazolam, ,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
Clonazepam, powder,
Species
human, rat
Flunitrazepam, ,
Species
human
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
Diazepam, ,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse, rabbit
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GABRD,
Species
human
MISSION® esiRNA, targeting mouse Gabrd,
Species
mouse