- Oxidative Addition Complexes as Precatalysts for Cross-Coupling Reactions Requiring Extremely Bulky Biarylphosphine Ligands.
Oxidative Addition Complexes as Precatalysts for Cross-Coupling Reactions Requiring Extremely Bulky Biarylphosphine Ligands.
Organic letters (2017-05-13)
Bryan T Ingoglia, Stephen L Buchwald
PMID28498667
ABSTRACT
In this report, we describe the application of palladium-based oxidative addition complexes (OACs) as effective precatalysts for C-N, C-O, and C-F cross-coupling reactions with a variety of (hetero)arenes. These complexes offer a convenient alternative to previously developed classes of precatalysts, particularly in the case of the bulkiest biarylphosphine ligands, for which palladacycle-based precatalysts do not readily form. The precatalysts described herein are easily prepared and stable to long-term storage under air.
MATERIALS
Product Number
Brand
Product Description
SKU
Pack Size
Availability
Price
Quantity
SKU
Pack Size
Availability
Price
Quantity
SKU
Pack Size
Availability
Price
Quantity
SKU
Pack Size
Availability
Price
Quantity