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S9637

Sigma-Aldrich

Sodium succinate dibasic hexahydrate

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym(s):

Butanedioic acid disodium salt, Succinic acid disodium salt

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About This Item

Linear Formula:
NaOOCCH2CH2COONa · 6H2O
CAS Number:
6106-21-4
Molecular Weight:
270.14
Beilstein:
3921044
EC Number:
205-778-7
MDL number:
MFCD00149117
UNSPSC Code:
12352207
PubChem Substance ID:
24899848
NACRES:
NA.71

product line

BioReagent

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

pH

8—9.5 (25 °C, 270 g/L)

solubility

H2O: 100 mg/mL, clear, colorless

SMILES string

O.O.O.O.O.O.[Na+].[Na+].[O-]C(=O)CCC([O-])=O

InChI

1S/C4H6O4.2Na.6H2O/c5-3(6)1-2-4(7)8;;;;;;;;/h1-2H2,(H,5,6)(H,7,8);;;6*1H2/q;2*+1;;;;;;/p-2

InChI key

ZBTUYCUNQBRXOR-UHFFFAOYSA-L

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General description

Sodium succinate dibasic hexahydrate is the sodium salt of succinic acid, a dicarboxylic acid. This versatile compound finds extensive use in cell biology, cell culture, and biochemical research applications. It serves as both an energy source and a buffer in cell culture and cell biology research, particularly within the Tricarboxylic Acid (TCA) or Krebs cycle. It is hypothesized that Sodium succinate dibasic hexahydrate acts as an ionophore, facilitating the transport of ions across cell membranes and thus influencing cellular metabolism. Also known as Succinic acid disodium salt, this product provides the necessary substrate for ATP (adenosine triphosphate) production, essential for optimal cellular function.

Application

Sodium succinate dibasic hexahydrate has been used:
  • as a supplement in the assay medium to incubate mitochondria to measure the specific activity of complex-II
  • as a component in plant induction medium/ protoplast induction media (PIM) for plant regeneration
  • as a small-molecule additive in the fresh medium to study its positive synergistic effects on transgene expression in Chinese hamster ovary (CHO) cells

Features and Benefits

  • Versatile and adaptable for a wide variety of laboratory and research applications
  • BioReagent Grade Sodium succinate for your Cell Biology and Biochemical research
  • Tested for Mammalian and Insect cell culture applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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