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EMU027811

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Usp2

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TCCTTCTGGATGGTCTCCACAATGAGGTGAACCGGGTGGCAGCAAGGCCTAAGGCCAGCCCTGAGACCCTTGATCATCTCCCTGATGAAGAAAAGGGGCGACAGATGTGGAGGAAGTATCTGGAAAGGGAAGACAGTCGGATTGGGGATCTCTTCGTTGGGCAGCTGAAGAGCTCCCTCACATGCACCGATTGTGGCTACTGCTCTACAGTCTTCGATCCCTTCTGGGATCTCTCGTTGCCCATCGCAAAGAGAGGTTACCCTGAGGTGACGTTAATGGATTGTATGAGGCTCTTCACCAAAGAGGACATATTGGATGGTGATGAGAAGCCAACTTGCTGCCGCTGCCGAGCCAGAAAACGATGCATAAAAAAGTTCTCTGTCCAGAGGTTCCCAAAGATCTTGGTGCTCCACCTGAAGCGATTCTCAGAATCCAGGATACGAACCAGCAAGCTCACAACA

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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B Wang et al.
Cell death and differentiation, 21(7), 1160-1169 (2014-04-29)
Mcl-1 is a unique antiapoptotic Bcl2 family member with a short half-life due to its rapid turnover through ubiquitination. We discovered that Ku70, a DNA double-strand break repair protein, functions as a deubiquitinase to stabilize Mcl-1. Ku70 knockout in mouse

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