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Merck

TPO

thyroid peroxidase

Synonyms:
MSA, TDH2A, TPX
Species:
UniProtKB ID:
Gene ID:
  • Human(7173) Summary: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
  • Mouse(22018) thyroid peroxidase
  • Rat(54314) thyroid peroxidase
  • cow(525013) thyroid peroxidase
  • naked mole-rat(101704548) thyroid peroxidase
  • domestic guinea pig(100723704) thyroid peroxidase
  • chicken(776120) thyroid peroxidase
  • domestic cat(101098706) thyroid peroxidase
  • dog(403521) thyroid peroxidase

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ELISA

Product Number
Description
Species
Human TPO / Thyroid Peroxidase ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TPO antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Thyroid Peroxidase Antibody, clone 3C4A4, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
Anti-Tpo Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-TPO antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-TPO Antibody, clone 47, ,
Species Reactivity
human
Application
ELISA
radioimmunoassay

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Methimazole, analytical standard,
Species
human
Methimazole, VETRANAL®, analytical standard,
Species
human
Thiamazole, European Pharmacopoeia (EP) Reference Standard,
Species
human
Methimazole, United States Pharmacopeia (USP) Reference Standard,
Species
human
2-Mercapto-1-methylimidazole, ≥99%,
Species
human

Proteins

Product Number
Description
Species
Thrombopoietin, TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation & maturation of megakaryocytes & promotes increased circulating levels of platelets in vivo.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TPO,
Species
human