Skip to Content
Merck

SPTLC1

serine palmitoyltransferase, long chain base subunit 1

Synonyms:
HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI
Species:
UniProtKB ID:
Gene ID:
  • Human(10558) Summary: Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(268656) serine palmitoyltransferase, long chain base subunit 1
  • Rat(361213) serine palmitoyltransferase, long chain base subunit 1
  • Zebrafish(553981) serine palmitoyltransferase, long chain base subunit 1
  • chicken(426145) serine palmitoyltransferase, long chain base subunit 1
  • domestic cat(101087947) serine palmitoyltransferase, long chain base subunit 1
  • dog(484192) serine palmitoyltransferase, long chain base subunit 1
  • cow(614165) serine palmitoyltransferase, long chain base subunit 1
  • sheep(101105721) serine palmitoyltransferase, long chain base subunit 1
  • Domestic Rabbit(100344536) serine palmitoyltransferase, long chain base subunit 1
  • naked mole-rat(101716616) serine palmitoyltransferase, long chain base subunit 1
  • domestic guinea pig(100726468) serine palmitoyltransferase, long chain base subunit 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SPTLC1 Antibody, serum, from rabbit,
Species Reactivity
chimpanzee, human
Application
western blot
Anti-SPTLC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-SPTLC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SPTLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-SPTLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SPTLC1,
Species
human