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Merck

SCN3A

sodium channel, voltage-gated, type III, alpha subunit

Synonyms:
NAC3, Nav1.3
Species:
UniProtKB ID:
Gene ID:
  • Human(6328) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20269) sodium channel, voltage-gated, type III, alpha
  • Rat(497770) sodium channel, voltage-gated, type III, alpha
  • domestic guinea pig(100715651) sodium channel, voltage-gated, type III, alpha subunit
  • naked mole-rat(101716077) sodium channel, voltage-gated, type III, alpha subunit
  • Domestic Rabbit(100349657) sodium channel, voltage-gated, type III, alpha subunit
  • cow(534223) sodium channel, voltage-gated, type III, alpha subunit
  • sheep(101103874) sodium channel, voltage-gated, type III, alpha subunit
  • chicken(424180) sodium channel, voltage-gated, type III, alpha subunit
  • dog(478772) sodium channel, voltage-gated, type III, alpha subunit
  • domestic cat(101082587) sodium channel, voltage-gated, type III, alpha subunit
  • Horse(100061941) sodium channel, voltage-gated, type III, alpha subunit

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SCN3A antibody produced in mouse, clone 2F8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-SCN3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Sodium Channel Antibody, Voltage Gated, Brain Type III, pain, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Species Reactivity
mammals
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Product Number
Description
Species
Mexiletine hydrochloride, powder,
Species
human
Prilocaine hydrochloride, ≥98% (TLC),
Species
human
Tetracaine, ≥98% (TLC),
Species
human
Tetracaine hydrochloride, ≥99%,
Species
human
Lidocaine hydrochloride monohydrate, solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Scn3a,
Species
mouse
MISSION® esiRNA, targeting human SCN3A,
Species
human