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Merck

HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10

Synonyms:
17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1
Species:
UniProtKB ID:
Gene ID:
  • Human(3028) Summary: This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(15108) hydroxysteroid (17-beta) dehydrogenase 10
  • Rat(63864) hydroxysteroid (17-beta) dehydrogenase 10
  • Zebrafish(450078) hydroxysteroid (17-beta) dehydrogenase 10
  • chicken(425758) hydroxysteroid (17-beta) dehydrogenase 10
  • cow(281809) hydroxysteroid (17-beta) dehydrogenase 10
  • domestic cat(101090672) hydroxysteroid (17-beta) dehydrogenase 10
  • dog(480930) hydroxysteroid (17-beta) dehydrogenase 10
  • domestic guinea pig(100718814) hydroxysteroid (17-beta) dehydrogenase 10
  • naked mole-rat(101712281) hydroxysteroid (17-beta) dehydrogenase 10
  • sheep(101119880) hydroxysteroid (17-beta) dehydrogenase 10

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HSD17B10 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-HSD17B10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-HSD17B10 Antibody, clone 5F3, clone 5F3, from mouse,
Species Reactivity
human, mouse
Application
electron microscopy
immunocytochemistry

immunohistochemistry

western blot
Anti-ERAB/HSD17B10 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot

Proteins

Product Number
Description
Species
HSD17B10, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Hsd17b10,
Species
mouse
MISSION® esiRNA, targeting human HSD17B10,
Species
human