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Merck

EHMT1

euchromatic histone-lysine N-methyltransferase 1

Synonyms:
EUHMTASE1, Eu-HMTase1, FP13812, GLP, GLP1, KMT1D, bA188C12.1
Species:
UniProtKB ID:
Gene ID:
  • Human(79813) Summary: The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(77683) euchromatic histone methyltransferase 1
  • Rat(362078) euchromatic histone-lysine N-methyltransferase 1
  • chicken(417250) euchromatic histone-lysine N-methyltransferase 1
  • dog(491224) euchromatic histone-lysine N-methyltransferase 1
  • domestic cat(101087111) euchromatic histone-lysine N-methyltransferase 1
  • cow(528606) euchromatic histone-lysine N-methyltransferase 1
  • Horse(100058869) euchromatic histone-lysine N-methyltransferase 1
  • sheep(101123545) euchromatic histone-lysine N-methyltransferase 1
  • domestic guinea pig(100735478) euchromatic histone-lysine N-methyltransferase 1
  • naked mole-rat(101699104) euchromatic histone-lysine N-methyltransferase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-EHMT1, (N-terminal) antibody produced in mouse, clone 1H2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-EHMT1/GLP1 Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-EHMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-EHMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Proteins

Product Number
Description
Species
EHMT1 human, recombinant, expressed in E. coli, ≥63% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human EHMT1,
Species
human
MISSION® esiRNA, targeting mouse Ehmt1,
Species
mouse