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  • Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases.

Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases.

Journal of the American Society for Mass Spectrometry (2017-09-25)
K Kulyk, O Rebrov, M Ryding, R D Thomas, E Uggerud, M Larsson
초록

Here we report on the gas-phase interactions between protonated enantiopure amino acids (L- and D-enantiomers of Met, Phe, and Trp) and chiral target gases [(R)- and (S)-2-butanol, and (S)-1-phenylethanol] in 0.1-10.0 eV low-energy collisions. Two major processes are seen to occur over this collision energy regime, collision-induced dissociation and ion-molecule complex formation. Both processes were found to be independent of the stereo-chemical composition of the interacting ions and targets. These data shed light on the currently debated mechanisms of gas-phase chiral selectivity by demonstrating the inapplicability of the three-point model to these interactions, at least under single collision conditions. Graphical Abstract.