- PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Cancer research (2017-08-19)
Lin Wang, Guanhua Song, Xiang Zhang, Tingting Feng, Jihong Pan, Weiwen Chen, Muyi Yang, Xinnuo Bai, Yu Pang, Jindan Yu, Jinxiang Han, Bo Han
PMID28819028
초록
Onset of castration-resistance prostate cancer (CRPC) after long-term androgen deprivation therapy remains a major obstacle in the treatment of prostate cancer. The peptidylarginine deiminase PADI2 has been implicated in chronic inflammatory diseases and cancer. Here we show that
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