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  • Dual-targeting Theranostic System with Mimicking Apoptosis to Promote Myocardial Infarction Repair

Dual-targeting Theranostic System with Mimicking Apoptosis to Promote Myocardial Infarction Repair

Theranostics (2017-11-22)
Jingli Chen, Jun Yang, Ruiyuan Liu, Chenmeng Qiao, Zhiguo Lu, Yuanjie Shi, Zhanming Fan, Zhenzhong Zhang, Xin Zhang
초록

Currently unsatisfactory treatment of myocardial infarction (MI) is due to the unbridled inflammation and the delayed diagnosis at the early stage. To address these problems, firstly, phosphatidylserine (PS) was used to modulate the phenotypes of macrophages (MΦ) and resolve the early inflammation

MATERIALS
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Sigma-Aldrich
2-Hydroxyethyl 2-bromoisobutyrate, 95%
Sigma-Aldrich
Oleic acid, technical grade, 90%
Sigma-Aldrich
Biphenyl-4-carboxylic acid, 95%
Sigma-Aldrich
N,N,N′,N′′,N′′-Pentamethyldiethylenetriamine, 99%
Sigma-Aldrich
(3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione, 98%
Sigma-Aldrich
3,3′-Diiodo-L-thyronine (T2) hydrochloride, 98% (CP)
Sigma-Aldrich
Tin(II) 2-ethylhexanoate, 92.5-100.0%
Sigma-Aldrich
α-Bromoisobutyryl bromide, 98%