- From small building blocks to complex molecular architecture.
From small building blocks to complex molecular architecture.
Organic letters (2006-03-28)
Eugene R Zubarev, Jun Xu, Jacob D Gibson, Arshad Sayyad
PMID16562893
초록
[reaction: see text] We describe a synthesis of a dendrimer-like amphiphile containing a flat rigid core and 12 hydrophobic and hydrophilic arms. We employ a modular approach based on stepwise protection chemistry starting from simple building blocks. The key feature of this approach is the absence of a polymerization step, which makes it applicable for linear monofunctionalized precursors of any kind. This strategy also allows for precise control of the number of arms and ensures their alternating arrangement.
MATERIALS