- Au(I)-catalyzed cyclization of enynes bearing an olefinic cycle.
Au(I)-catalyzed cyclization of enynes bearing an olefinic cycle.
The Journal of organic chemistry (2006-12-02)
Sang Ick Lee, Soo Min Kim, Mi Ra Choi, Sun Young Kim, Young Keun Chung, Won-Sik Han, Sang Ook Kang
PMID17137363
초록
Gold(I)-catalyzed cyclization of enynes containing an olefinic cycle has been studied. The introduction of an olefinic ring instead of a terminal alkene in enynes dramatically increased the yield of the reaction. Enynes having an olefinic cycle were prepared by a rhodium-catalyzed intermolecular [4 + 2] cycloaddition of diynes with butadiene. Consecutive rhodium-catalyzed Diels-Alder/gold(I)-catalyzed cycloisomerization reactions were integrated in a one-pot reaction.
MATERIALS