- Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.
Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.
Bioorganic & medicinal chemistry letters (2007-09-22)
Sébastien Guery, Philipp Floersheim, Klemens Kaupmann, Wolfgang Froestl
PMID17884493
초록
The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented.
MATERIALS